Version 5.4
Bos taurus Protein: SMARCA2
Summary
InnateDB Protein IDBP-683205.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SMARCA2
Protein Name probable global transcription activator SNF2L2
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000035551
InnateDB Gene IDBG-631631 (SMARCA2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 100 interaction(s) predicted by orthology.
Predicted by orthology
Total 100 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001105 RNA polymerase II transcription coactivator activity
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0004386 helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016817 hydrolase activity, acting on acid anhydrides
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
GO:0042393 histone binding
GO:0044212 transcription regulatory region DNA binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0008152 metabolic process
GO:0008285 negative regulation of cell proliferation
GO:0030308 negative regulation of cell growth
GO:0035887 aortic smooth muscle cell differentiation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0000790 nuclear chromatin
GO:0005634 nucleus
GO:0016514 SWI/SNF complex
GO:0043231 intracellular membrane-bounded organelle
GO:0045111 intermediate filament cytoskeleton
GO:0071564 npBAF complex
GO:0071565 nBAF complex
Protein Structure and Domains
PDB ID
InterPro IPR000330 SNF2-related
IPR001487 Bromodomain
IPR001650 Helicase, C-terminal
IPR006576 BRK domain
IPR012337 Ribonuclease H-like domain
IPR013999 HAS subgroup
IPR014001 Helicase, superfamily 1/2, ATP-binding domain
IPR014012 Helicase/SANT-associated, DNA binding
IPR014978 Glutamine-Leucine-Glutamine, QLQ
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00176
PF00439
PF00271
PF07533
PF07529
PF08880
PRINTS PR00503
PIRSF
SMART SM00297
SM00490
SM00592
SM00573
SM00487
SM00951
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL A5PKK5
UniProt Splice Variant
Entrez Gene 540904
UniGene Bt.63204
RefSeq NP_001092585
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC142521 DAAA02022747 DAAA02022748 DAAA02022749
GenPept AAI42522

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca