InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: NLRX1

Summary

InnateDB Protein

IDBP-683271.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NLRX1

Protein Name

NLR family member X1

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000016601

InnateDB Gene

IDBG-631720 (NLRX1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.

Predicted by orthology
Total	19 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0005515	protein binding
GO:0005524	ATP binding

Biological Process

GO:0032688	negative regulation of interferon-beta production
GO:0032715	negative regulation of interleukin-6 production
GO:0039536	negative regulation of RIG-I signaling pathway
GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045824	negative regulation of innate immune response
GO:0050728	negative regulation of inflammatory response

Cellular Component

GO:0005739

mitochondrion

Protein Structure and Domains

PDB ID

InterPro

IPR003590 Leucine-rich repeat, ribonuclease inhibitor subtype
IPR007111 NACHT nucleoside triphosphatase
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PRINTS

PIRSF

SMART

SM00368

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-