Version 5.4
Bos taurus Protein: KANK1
Summary
InnateDB Protein IDBP-683297.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KANK1
Protein Name KN motif and ankyrin repeat domains 1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000014571
InnateDB Gene IDBG-631680 (KANK1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008013 beta-catenin binding
Biological Process
GO:0010977 negative regulation of neuron projection development
GO:0030177 positive regulation of Wnt signaling pathway
GO:0030336 negative regulation of cell migration
GO:0030837 negative regulation of actin filament polymerization
GO:0035024 negative regulation of Rho protein signal transduction
GO:0035413 positive regulation of catenin import into nucleus
GO:0046627 negative regulation of insulin receptor signaling pathway
GO:0090303 positive regulation of wound healing
GO:1900025 negative regulation of substrate adhesion-dependent cell spreading
GO:1900028 negative regulation of ruffle assembly
GO:2000114 regulation of establishment of cell polarity
GO:2000393 negative regulation of lamellipodium morphogenesis
Cellular Component
GO:0032587 ruffle membrane
Protein Structure and Domains
PDB ID
InterPro IPR002110 Ankyrin repeat
IPR020683 Ankyrin repeat-containing domain
IPR021939 Kank N-terminal motif
PFAM PF00023
PF13606
PF11929
PF12796
PF12075
PRINTS PR01415
PIRSF
SMART SM00248
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1N1B8
UniProt Splice Variant
Entrez Gene 534869
UniGene Bt.111072
RefSeq XP_002689675
HUGO HGNC:19309
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02022777 DAAA02022778
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca