InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: CYP11A1

Summary

InnateDB Protein

IDBP-683426.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CYP11A1

Protein Name

cholesterol side-chain cleavage enzyme, mitochondrial precursor

Synonyms

CYP11A; CYPXIA1; P450(scc);

Species

Bos taurus

Ensembl Protein

ENSBTAP00000009106

InnateDB Gene

IDBG-631847 (CYP11A1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004497	monooxygenase activity
GO:0005506	iron ion binding
GO:0008386	cholesterol monooxygenase (side-chain-cleaving) activity
GO:0016491	oxidoreductase activity
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037	heme binding
GO:0046872	metal ion binding

Biological Process

GO:0006700	C21-steroid hormone biosynthetic process
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005739

mitochondrion

Protein Structure and Domains

PDB ID

InterPro

IPR001128 Cytochrome P450
IPR002397 Cytochrome P450, B-class
IPR002399 Cytochrome P450, mitochondrial
IPR002401 Cytochrome P450, E-class, group I
IPR002403 Cytochrome P450, E-class, group IV

PFAM

PF00067

PRINTS

PR00385
PR00359
PR00408
PR00463
PR00465

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite