InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: GTF2H3

Summary

InnateDB Protein

IDBP-683770.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GTF2H3

Protein Name

ral transcription factor IIH subunit 3

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000009561

InnateDB Gene

IDBG-632172 (GTF2H3)

Protein Structure

UniProt Annotation

Function

Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. Anchors XPB (By similarity). {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.

Predicted by orthology
Total	12 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004672	protein kinase activity
GO:0008094	DNA-dependent ATPase activity
GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity
GO:0046872	metal ion binding
GO:0047485	protein N-terminus binding

Biological Process

GO:0006200	ATP catabolic process
GO:0006281	DNA repair
GO:0006289	nucleotide-excision repair
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0006366	transcription from RNA polymerase II promoter
GO:0006468	protein phosphorylation
GO:0006974	cellular response to DNA damage stimulus