Version 5.4
Bos taurus Protein: PIGC
Summary
InnateDB Protein IDBP-683849.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PIGC
Protein Name Phosphatidylinositol N-acetylglucosaminyltransferase subunit C
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000034036
InnateDB Gene IDBG-632247 (PIGC)
Protein Structure
UniProt Annotation
Function Part of the complex catalyzing the transfer of N- acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis. {ECO:0000250}.
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016740 transferase activity
GO:0016757 transferase activity, transferring glycosyl groups
GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity
Biological Process
GO:0006506 GPI anchor biosynthetic process
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR009450 Phosphatidylinositol N-acetylglucosaminyltransferase subunit C
PFAM PF06432
PRINTS
PIRSF PIRSF016104
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3ZBX1
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 510483
UniGene Bt.49348
RefSeq NP_001029555
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC103058
GenPept AAI03059

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca