Version 5.4
Bos taurus Protein: ALDH1A1
Summary
InnateDB Protein IDBP-683893.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ALDH1A1
Protein Name Retinal dehydrogenase 1
Synonyms ALDH1;
Species Bos taurus
Ensembl Protein ENSBTAP00000010661
InnateDB Gene IDBG-632280 (ALDH1A1)
Protein Structure
UniProt Annotation
Function Binds free retinal and cellular retinol-binding protein- bound retinal. Can convert/oxidize retinaldehyde to retinoic acid (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001758 retinal dehydrogenase activity
GO:0003995 acyl-CoA dehydrogenase activity
GO:0004029 aldehyde dehydrogenase (NAD) activity
GO:0016491 oxidoreductase activity
GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
Biological Process
GO:0008152 metabolic process
GO:0008218 bioluminescence
GO:0042572 retinol metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR008670 Acyl-CoA reductase, LuxC
IPR015590 Aldehyde dehydrogenase domain
IPR016161 Aldehyde/histidinol dehydrogenase
PFAM PF05893
PF00171
PRINTS
PIRSF PIRSF009414
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P48644
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 281615
UniGene Bt.4732
RefSeq NP_776664
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC105193 BT030667 L36128
GenPept AAA74234 AAI05194 ABS44983

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca