InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: BT.70631

Summary

InnateDB Protein

IDBP-683914.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.70631

Protein Name

annexin A1

Synonyms

p35;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000021256

InnateDB Gene

IDBG-632306 (BT.70631)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 49 interaction(s) predicted by orthology.

Predicted by orthology
Total	49 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004859	phospholipase inhibitor activity
GO:0005198	structural molecule activity
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0005544	calcium-dependent phospholipid binding
GO:0019834	phospholipase A2 inhibitor activity
GO:0030674	protein binding, bridging
GO:0048306	calcium-dependent protein binding

Biological Process

GO:0001780	neutrophil homeostasis
GO:0007165	signal transduction
GO:0018149	peptide cross-linking
GO:0030216	keratinocyte differentiation
GO:0031340	positive regulation of vesicle fusion
GO:0033031	positive regulation of neutrophil apoptotic process
GO:0042127	regulation of cell proliferation
GO:0043086	negative regulation of catalytic activity
GO:0046632	alpha-beta T cell differentiation
GO:0050482	arachidonic acid secretion
GO:0071385	cellular response to glucocorticoid stimulus
GO:0097350	neutrophil clearance
GO:1900087	positive regulation of G1/S transition of mitotic cell cycle
GO:2000483	negative regulation of interleukin-8 secretion

Cellular Component

GO:0001533	cornified envelope
GO:0005615	extracellular space
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005886	plasma membrane
GO:0009986	cell surface
GO:0042383	sarcolemma
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR001464 Annexin
IPR002388 Annexin, type I
IPR018502 Annexin repeat

PFAM

PF00191

PRINTS

PR00196
PR00197

PIRSF

SMART

SM00335

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

F1N650

UniProt Splice Variant

Entrez Gene

327662

UniGene

Bt.70631

RefSeq

NP_786978

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

DAAA02022893 DAAA02022894

GenPept