Version 5.4
Homo sapiens Protein: LILRB5
Summary
InnateDB Protein IDBP-68395.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LILRB5
Protein Name leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5
Synonyms CD85C; LIR-8; LIR8;
Species Homo sapiens
Ensembl Protein ENSP00000320390
InnateDB Gene IDBG-68391 (LILRB5)
Protein Structure
UniProt Annotation
Function May act as receptor for class I MHC antigens.
Subcellular Localization Membrane; Single-pass type I membrane protein.
Disease Associations
Tissue Specificity Detected in a natural killer (NK) cells. {ECO:0000269PubMed:9548455}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004888 transmembrane signaling receptor activity
GO:0005515 protein binding
Biological Process
GO:0002376 immune system process
GO:0006952 defense response
GO:0007166 cell surface receptor signaling pathway
Cellular Component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
PFAM
PRINTS
PIRSF
SMART SM00408
SM00409
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O75023
PhosphoSite PhosphoSite-O75023
TrEMBL
UniProt Splice Variant
Entrez Gene 10990
UniGene Hs.655338
RefSeq NP_006831
HUGO HGNC:6609
OMIM 604814
CCDS CCDS12885
HPRD 11993
IMGT
EMBL AC010492 AF025534 AK057072 AK223296 BC025704
GenPept AAB87668 AAH25704 BAB71361

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca