InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: MYOD1

Summary

InnateDB Protein

IDBP-683971.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MYOD1

Protein Name

myoblast determination protein 1

Synonyms

MyoD;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000002868

InnateDB Gene

IDBG-632365 (MYOD1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 87 interaction(s) predicted by orthology.

Predicted by orthology
Total	87 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001047	core promoter binding
GO:0001228	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0008134	transcription factor binding
GO:0019899	enzyme binding
GO:0031490	chromatin DNA binding
GO:0031625	ubiquitin protein ligase binding
GO:0035257	nuclear hormone receptor binding
GO:0043565	sequence-specific DNA binding
GO:0046982	protein heterodimerization activity
GO:0046983	protein dimerization activity

Biological Process

GO:0000381	regulation of alternative mRNA splicing, via spliceosome
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0007517	muscle organ development
GO:0007518	myoblast cell fate determination
GO:0007519	skeletal muscle tissue development
GO:0009267	cellular response to starvation
GO:0014904	myotube cell development
GO:0014908	myotube differentiation involved in skeletal muscle regeneration
GO:0043415	positive regulation of skeletal muscle tissue regeneration
GO:0043484	regulation of RNA splicing
GO:0043503	skeletal muscle fiber adaptation
GO:0043966	histone H3 acetylation
GO:0043967	histone H4 acetylation
GO:0045445	myoblast differentiation
GO:0045893	positive regulation of transcription, DNA-templated
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0048741	skeletal muscle fiber development
GO:0051146	striated muscle cell differentiation
GO:0051149	positive regulation of muscle cell differentiation
GO:0071385	cellular response to glucocorticoid stimulus
GO:0071392	cellular response to estradiol stimulus
GO:0071453	cellular response to oxygen levels
GO:1901741	positive regulation of myoblast fusion

Cellular Component

GO:0000790	nuclear chromatin
GO:0005634	nucleus
GO:0005667	transcription factor complex
GO:0005737	cytoplasm
GO:0030016	myofibril

Protein Structure and Domains

PDB ID

InterPro

IPR002546 Myogenic basic muscle-specific protein
IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
IPR022032 Myogenic determination factor 5

PFAM

PF01586
PF00010
PF12232

PRINTS

PIRSF

SMART

SM00520
SM00353

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q0VBX9

UniProt Splice Variant

Entrez Gene

281938

UniGene

Bt.13078

RefSeq

NP_001035568

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

AF093675 BC120454 DAAA02040581

GenPept

AAC63373 AAI20455