Version 5.4
Bos taurus Protein: ADAR
Summary
InnateDB Protein IDBP-684037.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ADAR
Protein Name adenosine deaminase, RNA-specific
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000009896
InnateDB Gene IDBG-632405 (ADAR)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
Predicted by orthology
Total 15 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0003726 double-stranded RNA adenosine deaminase activity
GO:0004000 adenosine deaminase activity
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0001701 in utero embryonic development
GO:0006382 adenosine to inosine editing
GO:0006396 RNA processing
GO:0006606 protein import into nucleus
GO:0006611 protein export from nucleus
GO:0009615 response to virus
GO:0016553 base conversion or substitution editing
GO:0035455 response to interferon-alpha
GO:0043066 negative regulation of apoptotic process
GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation
GO:0045070 positive regulation of viral genome replication
GO:0045071 negative regulation of viral genome replication
GO:0051607 defense response to virus
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0016020 membrane
GO:0044530 supraspliceosomal complex
Protein Structure and Domains
PDB ID
InterPro IPR000607 Double-stranded RNA-specific adenosine deaminase (DRADA)
IPR002466 Adenosine deaminase/editase
IPR014720 Double-stranded RNA-binding domain
PFAM PF02295
PF02137
PF00035
PRINTS
PIRSF
SMART SM00550
SM00552
SM00358
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1MUM9
UniProt Splice Variant
Entrez Gene 505134
UniGene
RefSeq XP_005197744
HUGO HGNC:225
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02007166
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca