InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: PIK3C2A

Summary

InnateDB Protein

IDBP-684348.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PIK3C2A

Protein Name

phosphoinositide-3-kinase, class 2, alpha polypeptide

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000043907

InnateDB Gene

IDBG-632709 (PIK3C2A)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.

Predicted by orthology
Total	22 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0016303	1-phosphatidylinositol-3-kinase activity
GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity

Biological Process

GO:0006897	endocytosis
GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process
GO:0046854	phosphatidylinositol phosphorylation
GO:0048015	phosphatidylinositol-mediated signaling

Cellular Component

GO:0005737	cytoplasm
GO:0005886	plasma membrane
GO:0005942	phosphatidylinositol 3-kinase complex
GO:0016020	membrane
GO:0031982	vesicle
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR000008 C2 domain
IPR000341 Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain
IPR002420 Phosphatidylinositol 3-kinase, C2 domain
IPR029071 Ubiquitin-related domain

PFAM

PF00168
PF00794
PF00792

PRINTS

PR00360

PIRSF

SMART

SM00239
SM00144
SM00142

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt