InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: PRPF8

Summary

InnateDB Protein

IDBP-684534.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PRPF8

Protein Name

pre-mRNA-processing-splicing factor 8

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000043577

InnateDB Gene

IDBG-632840 (PRPF8)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 107 interaction(s) predicted by orthology.

Predicted by orthology
Total	107 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0003723	RNA binding
GO:0005515	protein binding
GO:0017070	U6 snRNA binding
GO:0030623	U5 snRNA binding
GO:0044822	poly(A) RNA binding
GO:0046982	protein heterodimerization activity

Biological Process

GO:0000398

mRNA splicing, via spliceosome

Cellular Component

GO:0005634	nucleus
GO:0005681	spliceosomal complex
GO:0016020	membrane
GO:0071013	catalytic step 2 spliceosome

Protein Structure and Domains

PDB ID

InterPro

IPR000555 JAB1/MPN/MOV34 metalloenzyme domain
IPR008972 Cupredoxin
IPR009072 Histone-fold
IPR012591 PRO8NT domain
IPR012592 PROCN domain
IPR012984 PROCT domain
IPR019580 Pre-mRNA-processing-splicing factor 8, U6-snRNA-binding
IPR019581 Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding
IPR019582 RNA recognition motif, spliceosomal PrP8
IPR021983 PRP8 domain IV core

PFAM