InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: HPD

Summary

InnateDB Protein

IDBP-684564.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

HPD

Protein Name

4-hydroxyphenylpyruvate dioxygenase

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000005469

InnateDB Gene

IDBG-632894 (HPD)

Protein Structure

UniProt Annotation

Function

Key enzyme in the degradation of tyrosine. {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003868	4-hydroxyphenylpyruvate dioxygenase activity
GO:0016491	oxidoreductase activity
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen
GO:0046872	metal ion binding
GO:0051213	dioxygenase activity

Biological Process

GO:0006559	L-phenylalanine catabolic process
GO:0006572	tyrosine catabolic process
GO:0009072	aromatic amino acid family metabolic process
GO:0055114	oxidation-reduction process

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain
IPR005956 4-hydroxyphenylpyruvate dioxygenase
IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase

PFAM

PF00903

PRINTS

PIRSF

PIRSF009283

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q5EA20