Version 5.4
Bos taurus Protein: S100A10
Summary
InnateDB Protein IDBP-684648.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol S100A10
Protein Name Protein S100-A10
Synonyms p11;
Species Bos taurus
Ensembl Protein ENSBTAP00000020150
InnateDB Gene IDBG-632987 (S100A10)
Protein Structure
UniProt Annotation
Function Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine- specific kinase.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 30 interaction(s) predicted by orthology.
Predicted by orthology
Total 30 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0042803 protein homodimerization activity
GO:0044325 ion channel binding
Biological Process
GO:0001765 membrane raft assembly
GO:0006900 membrane budding
GO:0032855 positive regulation of Rac GTPase activity
GO:0051099 positive regulation of binding
GO:0051290 protein heterotetramerization
GO:0051496 positive regulation of stress fiber assembly
GO:0051894 positive regulation of focal adhesion assembly
GO:0071229 cellular response to acid
GO:0090002 establishment of protein localization to plasma membrane
GO:1900026 positive regulation of substrate adhesion-dependent cell spreading
Cellular Component
GO:0019897 extrinsic component of plasma membrane
GO:0045121 membrane raft
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR013787 S100/CaBP-9k-type, calcium binding, subdomain
PFAM PF01023
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P60902
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 282466
UniGene
RefSeq NP_777075
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AY911333 BC102207 M16464
GenPept AAA30423 AAI02208 AAW82101

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca