InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: BT.49360

Summary

InnateDB Protein

IDBP-684660.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.49360

Protein Name

nuclear receptor ROR-gamma

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000041645

InnateDB Gene

IDBG-632995 (BT.49360)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 37 interaction(s) predicted by orthology.

Predicted by orthology
Total	37 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001223	transcription coactivator binding
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0003707	steroid hormone receptor activity
GO:0004879	ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0005515	protein binding
GO:0008142	oxysterol binding
GO:0008270	zinc ion binding
GO:0043565	sequence-specific DNA binding
GO:0046872	metal ion binding
GO:0098531	direct ligand regulated sequence-specific DNA binding transcription factor activity

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0006468	protein phosphorylation
GO:0006805	xenobiotic metabolic process
GO:0010906	regulation of glucose metabolic process
GO:0019218	regulation of steroid metabolic process
GO:0030154	cell differentiation
GO:0030522	intracellular receptor signaling pathway
GO:0032922	circadian regulation of gene expression
GO:0033077	T cell differentiation in thymus
GO:0036315	cellular response to sterol
GO:0042093	T-helper cell differentiation
GO:0042753	positive regulation of circadian rhythm
GO:0043401	steroid hormone mediated signaling pathway
GO:0045586	regulation of gamma-delta T cell differentiation
GO:0045598	regulation of fat cell differentiation
GO:0046632	alpha-beta T cell differentiation
GO:0048535	lymph node development
GO:0048537	mucosal-associated lymphoid tissue development
GO:0048541	Peyer's patch development
GO:0060612	adipose tissue development
GO:0060850	regulation of transcription involved in cell fate commitment
GO:0070244	negative regulation of thymocyte apoptotic process
GO:0072539	T-helper 17 cell differentiation

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

InterPro

IPR000536 Nuclear hormone receptor, ligand-binding, core
IPR001628 Zinc finger, nuclear hormone receptor-type
IPR001723 Steroid hormone receptor
IPR003079 Nuclear receptor ROR
IPR008946 Nuclear hormone receptor, ligand-binding

PFAM

PF00104
PF00105

PRINTS

PR00047
PR00398
PR01293

PIRSF

SMART

SM00430
SM00399

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt