InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: KDM2B

Summary

InnateDB Protein

IDBP-684669.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

KDM2B

Protein Name

lysine (K)-specific demethylase 2B

Synonyms

FBXL10;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000003003

InnateDB Gene

IDBG-632962 (KDM2B)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 28 interaction(s) predicted by orthology.

Predicted by orthology
Total	28 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0046872	metal ion binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0007283	spermatogenesis
GO:0021555	midbrain-hindbrain boundary morphogenesis
GO:0021592	fourth ventricle development
GO:0021670	lateral ventricle development
GO:0021678	third ventricle development
GO:0021993	initiation of neural tube closure
GO:0030900	forebrain development
GO:0030901	midbrain development
GO:0030902	hindbrain development
GO:0035518	histone H2A monoubiquitination
GO:0043524	negative regulation of neuron apoptotic process
GO:0048596	embryonic camera-type eye morphogenesis
GO:2000178	negative regulation of neural precursor cell proliferation

Cellular Component

GO:0005634	nucleus
GO:0031519	PcG protein complex

Protein Structure and Domains

PDB ID

InterPro

IPR001810 F-box domain
IPR001965 Zinc finger, PHD-type
IPR002857 Zinc finger, CXXC-type
IPR003347 JmjC domain
IPR006553 Leucine-rich repeat, cysteine-containing subtype
IPR011011 Zinc finger, FYVE/PHD-type
IPR019787 Zinc finger, PHD-finger

PFAM