InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: MASP2

Summary

InnateDB Protein

IDBP-684745.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MASP2

Protein Name

mannan-binding lectin serine peptidase 2

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000017013

InnateDB Gene

IDBG-633071 (MASP2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001855	complement component C4b binding
GO:0003824	catalytic activity
GO:0004252	serine-type endopeptidase activity
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0008233	peptidase activity
GO:0016787	hydrolase activity
GO:0048306	calcium-dependent protein binding

Biological Process

GO:0001867	complement activation, lectin pathway
GO:0006508	proteolysis
GO:0006956	complement activation

Cellular Component

GO:0005576	extracellular region
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR000436 Sushi/SCR/CCP
IPR000742 Epidermal growth factor-like domain
IPR000859 CUB domain
IPR001254 Peptidase S1
IPR001314 Peptidase S1A, chymotrypsin-type
IPR001881 EGF-like calcium-binding domain
IPR009003 Trypsin-like cysteine/serine peptidase domain

PFAM

PF00084
PF00008
PF00431
PF00089
PF07645

PRINTS

PR00722

PIRSF

SMART

SM00032
SM00181
SM00042
SM00020
SM00179

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt