Version 5.4
Bos taurus Protein: AGPAT1
Summary
InnateDB Protein IDBP-684804.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AGPAT1
Protein Name 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha
Synonyms LPAAT;
Species Bos taurus
Ensembl Protein ENSBTAP00000005821
InnateDB Gene IDBG-633119 (AGPAT1)
Protein Structure
UniProt Annotation
Function Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.
Subcellular Localization Endoplasmic reticulum membrane; Multi-pass membrane protein.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity
GO:0016740 transferase activity
GO:0016746 transferase activity, transferring acyl groups
Biological Process
GO:0001819 positive regulation of cytokine production
GO:0006629 lipid metabolic process
GO:0006654 phosphatidic acid biosynthetic process
GO:0008152 metabolic process
GO:0008654 phospholipid biosynthetic process
GO:0016024 CDP-diacylglycerol biosynthetic process
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR002123 Phospholipid/glycerol acyltransferase
IPR004552 1-acyl-sn-glycerol-3-phosphate acyltransferase
PFAM PF01553
PRINTS
PIRSF
SMART SM00563
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q95JH2
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 282137
UniGene Bt.1541
RefSeq NP_803484
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AF281677 AF285100 BC115999
GenPept AAI16000 AAK58832 AAK69168

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca