InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: AGPAT1

Summary

InnateDB Gene

IDBG-633119.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

AGPAT1

Gene Name

1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

Synonyms

LPAAT

Species

Bos taurus

Ensembl Gene

ENSBTAG00000004442

Encoded Proteins

IDBP-684804

1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000204310:
This gene encodes an enzyme that converts lysophosphatidic acid (LPA) into phosphatidic acid (PA). LPA and PA are two phospholipids involved in signal transduction and in lipid biosynthesis in cells. This enzyme localizes to the endoplasmic reticulum. This gene is located in the class III region of the human major histocompatibility complex. Alternative splicing results in two transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 23:27017065-27024545

Strand

Forward strand

Band

Transcripts

ENSBTAT00000005821

ENSBTAP00000005821

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity
GO:0016740	transferase activity
GO:0016746	transferase activity, transferring acyl groups

Biological Process

GO:0001819	positive regulation of cytokine production
GO:0006629	lipid metabolic process
GO:0006654	phosphatidic acid biosynthetic process
GO:0008152	metabolic process
GO:0008654	phospholipid biosynthetic process
GO:0016024	CDP-diacylglycerol biosynthetic process