InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: PDIA3

Summary

InnateDB Protein

IDBP-684952.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PDIA3

Protein Name

protein disulfide-isomerase A3 precursor

Synonyms

GRP58;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000022854

InnateDB Gene

IDBG-633244 (PDIA3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 59 interaction(s) predicted by orthology.

Predicted by orthology
Total	59 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003756	protein disulfide isomerase activity
GO:0005515	protein binding
GO:0016853	isomerase activity
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006457	protein folding
GO:0034976	response to endoplasmic reticulum stress
GO:0045454	cell redox homeostasis
GO:2001238	positive regulation of extrinsic apoptotic signaling pathway

Cellular Component

GO:0005634	nucleus
GO:0005783	endoplasmic reticulum
GO:0009986	cell surface
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR005788 Disulphide isomerase
IPR005792 Protein disulphide isomerase
IPR012336 Thioredoxin-like fold
IPR013766 Thioredoxin domain

PFAM

PF13098
PF13192
PF13462
PF13905
PF00085

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

A5D7E8

UniProt Splice Variant

Entrez Gene

281803

UniGene

Bt.2562

RefSeq

NP_776758

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC140529 DAAA02052969

GenPept

AAI40530