Version 5.4
Bos taurus Protein: LSM5
Summary
InnateDB Protein IDBP-685018.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LSM5
Protein Name U6 snRNA-associated Sm-like protein LSm5
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000003010
InnateDB Gene IDBG-633320 (LSM5)
Protein Structure
UniProt Annotation
Function Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA, thereby facilitating formation of the spliceosomal U4/U6 duplex in vitro (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
Predicted by orthology
Total 18 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0006397 mRNA processing
GO:0008380 RNA splicing
Cellular Component
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0030529 ribonucleoprotein complex
Protein Structure and Domains
PDB ID
InterPro IPR001163 Ribonucleoprotein LSM domain
IPR006649 Ribonucleoprotein LSM domain, eukaryotic/archaea-type
IPR010920 Like-Sm (LSM) domain
PFAM PF01423
PRINTS
PIRSF
SMART SM00651
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q2HJH0
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 615136
UniGene Bt.43458
RefSeq NP_001040018
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC105404
GenPept AAI05405

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca