Bos taurus Protein: BT.58314
Summary
InnateDB Protein IDBP-685033.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.58314
Protein Name suppressor of cytokine signaling 5
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000011826
InnateDB Gene IDBG-633338 (BT.58314)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005154 epidermal growth factor receptor binding
GO:0005515 protein binding
GO:0030971 receptor tyrosine kinase binding
Biological Process
GO:0007173 epidermal growth factor receptor signaling pathway
GO:0007175 negative regulation of epidermal growth factor-activated receptor activity
GO:0007259 JAK-STAT cascade
GO:0016567 protein ubiquitination
GO:0019221 cytokine-mediated signaling pathway
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0035556 intracellular signal transduction
GO:0045627 positive regulation of T-helper 1 cell differentiation
GO:0045629 negative regulation of T-helper 2 cell differentiation
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000980 SH2 domain
IPR001496 SOCS protein, C-terminal
IPR022252 SOCS4/SOCS5 domain
PFAM PF00017
PF14633
PF07525
PF12610
PRINTS PR00401
PIRSF
SMART SM00252
SM00253
SM00969
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1MWV6
UniProt Splice Variant
Entrez Gene 514773
UniGene Bt.58314
RefSeq NP_001039647
HUGO HGNC:16852
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02030726 DAAA02030727
GenPept