Version 5.4
Bos taurus Protein: P2RX1
Summary
InnateDB Protein IDBP-685151.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol P2RX1
Protein Name purinergic receptor P2X, ligand-gated ion channel, 1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000009437
InnateDB Gene IDBG-633428 (P2RX1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0001614 purinergic nucleotide receptor activity
GO:0004931 extracellular ATP-gated cation channel activity
GO:0005216 ion channel activity
GO:0005261 cation channel activity
GO:0005524 ATP binding
Biological Process
GO:0002554 serotonin secretion by platelet
GO:0003056 regulation of vascular smooth muscle contraction
GO:0006810 transport
GO:0006811 ion transport
GO:0006812 cation transport
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006940 regulation of smooth muscle contraction
GO:0007320 insemination
GO:0010033 response to organic substance
GO:0019229 regulation of vasoconstriction
GO:0030168 platelet activation
GO:0033198 response to ATP
GO:0034220 ion transmembrane transport
GO:0035590 purinergic nucleotide receptor signaling pathway
GO:0043270 positive regulation of ion transport
GO:0046513 ceramide biosynthetic process
GO:0051924 regulation of calcium ion transport
Cellular Component
GO:0005639 integral component of nuclear inner membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031240 external side of cell outer membrane
GO:0045211 postsynaptic membrane
Protein Structure and Domains
PDB ID
InterPro IPR001429 P2X purinoreceptor
IPR003044 P2X1 purinoceptor
PFAM PF00864
PRINTS PR01307
PR01308
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E1BIP1
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq
HUGO HGNC:8533
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02048693
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca