Version 5.4
Bos taurus Protein: TAX1BP1
Summary
InnateDB Protein IDBP-685259.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TAX1BP1
Protein Name Tax1-binding protein 1 homolog
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000033573
InnateDB Gene IDBG-633540 (TAX1BP1)
Protein Structure
UniProt Annotation
Function Inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degraded by caspase-3-like family proteins upon TNF-induced apoptosis. May also play a role in the pro-inflammatory cytokine IL-1 signaling cascade (By similarity). {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 28 interaction(s) predicted by orthology.
Predicted by orthology
Total 28 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019900 kinase binding
Biological Process
GO:0006915 apoptotic process
GO:0032088 negative regulation of NF-kappaB transcription factor activity
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR012852 Coiled-coil transcriptional coactivator-like
PFAM PF07888
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q2KJE0
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 535589
UniGene Bt.17392
RefSeq NP_001039874
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC105389
GenPept AAI05390

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca