Homo sapiens Protein: NRP1
Summary
InnateDB Protein IDBP-68544.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NRP1
Protein Name neuropilin 1
Synonyms BDCA4; CD304; NP1; NRP; VEGF165R;
Species Homo sapiens
Ensembl Protein ENSP00000363956
InnateDB Gene IDBG-68532 (NRP1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 29 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 29 [view]
Protein-Protein 29 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005021 vascular endothelial growth factor-activated receptor activity
GO:0017154 semaphorin receptor activity
GO:0019838 growth factor binding
GO:0046872 metal ion binding
Biological Process
GO:0001525 angiogenesis
GO:0007155 cell adhesion
GO:0007411 axon guidance
GO:0009887 organ morphogenesis
GO:0035767 endothelial cell chemotaxis
GO:0038084 vascular endothelial growth factor signaling pathway
GO:0048010 vascular endothelial growth factor receptor signaling pathway
GO:0071526 semaphorin-plexin signaling pathway
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000421 Coagulation factor 5/8 C-terminal type domain
IPR000859 CUB domain
IPR008979 Galactose-binding domain-like
IPR014648 Neuropilin
PFAM PF00754
PF00431
PRINTS
PIRSF PIRSF036960
SMART SM00231
SM00042
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q9H2E0
UniProt Splice Variant
Entrez Gene 8829
UniGene Hs.131704
RefSeq
HUGO HGNC:8004
OMIM 602069
CCDS
HPRD 03642
IMGT
EMBL AF280548 AF280549 AF482431 AL121748 AL353600 AL833608
GenPept AAG41893 AAG41894 AAP78927 CAH10397