Bos taurus Protein: BT.103132
Summary
InnateDB Protein IDBP-685496.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.103132
Protein Name gap junction alpha-5 protein
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000008837
InnateDB Gene IDBG-633767 (BT.103132)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0055077 gap junction hemi-channel activity
GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling
GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling
Biological Process
GO:0001501 skeletal system development
GO:0001525 angiogenesis
GO:0001568 blood vessel development
GO:0003071 renal system process involved in regulation of systemic arterial blood pressure
GO:0003073 regulation of systemic arterial blood pressure
GO:0003151 outflow tract morphogenesis
GO:0003161 cardiac conduction system development
GO:0003174 mitral valve development
GO:0003193 pulmonary valve formation
GO:0003281 ventricular septum development
GO:0003283 atrial septum development
GO:0003284 septum primum development
GO:0003294 atrial ventricular junction remodeling
GO:0007154 cell communication
GO:0016264 gap junction assembly
GO:0030326 embryonic limb morphogenesis
GO:0035050 embryonic heart tube development
GO:0035922 foramen ovale closure
GO:0042312 regulation of vasodilation
GO:0048844 artery morphogenesis
GO:0055085 transmembrane transport
GO:0055117 regulation of cardiac muscle contraction
GO:0060307 regulation of ventricular cardiac muscle cell membrane repolarization
GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization
GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization
GO:0060412 ventricular septum morphogenesis
GO:0060413 atrial septum morphogenesis
GO:0061337 cardiac conduction
GO:0086005 ventricular cardiac muscle cell action potential
GO:0086014 atrial cardiac muscle cell action potential
GO:0086015 SA node cell action potential
GO:0086053 AV node cell to bundle of His cell communication by electrical coupling
GO:0086064 cell communication by electrical coupling involved in cardiac conduction
GO:0086065 cell communication involved in cardiac conduction
GO:0086067 AV node cell to bundle of His cell communication
GO:0086069 bundle of His cell to Purkinje myocyte communication
GO:0086091 regulation of heart rate by cardiac conduction
GO:1900133 regulation of renin secretion into blood stream
GO:1900825 regulation of membrane depolarization during cardiac muscle cell action potential
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005921 gap junction
GO:0005922 connexon complex
GO:0014704 intercalated disc
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030054 cell junction
Protein Structure and Domains
PDB ID
InterPro IPR000500 Connexin
IPR002264 Gap junction alpha-5 protein (Cx40)
IPR013092 Connexin, N-terminal
IPR019570 Gap junction protein, cysteine-rich domain
PFAM PF00029
PF10582
PRINTS PR00206
PR01135
PIRSF
SMART SM00037
SM01089
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1MHC7
UniProt Splice Variant
Entrez Gene 539491
UniGene Bt.103132
RefSeq NP_001071490
HUGO HGNC:4279
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02007326 DAAA02007327
GenPept