Version 5.4
Bos taurus Gene: BT.103132
Summary
InnateDB Gene IDBG-633767.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.103132
Gene Name gap junction alpha-5 protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000006720
Encoded Proteins
IDBP-685496
gap junction alpha-5 protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog null:
This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene may be associated with atrial fibrillation. Alternatively spliced transcript variants encoding the same isoform have been described. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:21983348-21999397
Strand Forward strand
Band
Transcripts
ENSBTAT00000008837 ENSBTAP00000008837
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0055077 gap junction hemi-channel activity
GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling
GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling
Biological Process
GO:0001501 skeletal system development
GO:0001525 angiogenesis
GO:0001568 blood vessel development
GO:0003071 renal system process involved in regulation of systemic arterial blood pressure
GO:0003073 regulation of systemic arterial blood pressure
GO:0003151 outflow tract morphogenesis
GO:0003161 cardiac conduction system development
GO:0003174 mitral valve development
GO:0003193 pulmonary valve formation
GO:0003281 ventricular septum development
GO:0003283 atrial septum development
GO:0003284 septum primum development
GO:0003294 atrial ventricular junction remodeling
GO:0007154 cell communication
GO:0016264 gap junction assembly
GO:0030326 embryonic limb morphogenesis
GO:0035050 embryonic heart tube development
GO:0035922 foramen ovale closure
GO:0042312 regulation of vasodilation
GO:0048844 artery morphogenesis
GO:0055085 transmembrane transport
GO:0055117 regulation of cardiac muscle contraction
GO:0060307 regulation of ventricular cardiac muscle cell membrane repolarization
GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization
GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization
GO:0060412 ventricular septum morphogenesis
GO:0060413 atrial septum morphogenesis
GO:0061337 cardiac conduction
GO:0086005 ventricular cardiac muscle cell action potential
GO:0086014 atrial cardiac muscle cell action potential
GO:0086015 SA node cell action potential
GO:0086053 AV node cell to bundle of His cell communication by electrical coupling
GO:0086064 cell communication by electrical coupling involved in cardiac conduction
GO:0086065 cell communication involved in cardiac conduction
GO:0086067 AV node cell to bundle of His cell communication
GO:0086069 bundle of His cell to Purkinje myocyte communication
GO:0086091 regulation of heart rate by cardiac conduction
GO:1900133 regulation of renin secretion into blood stream
GO:1900825 regulation of membrane depolarization during cardiac muscle cell action potential
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005921 gap junction
GO:0005922 connexon complex
GO:0014704 intercalated disc
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030054 cell junction
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
null
View Gene Order
ENSMUSG00000057123
View Gene Order
Cross-References
SwissProt
TrEMBL F1MHC7
UniProt Splice Variant
Entrez Gene 539491
UniGene Bt.103132
RefSeq NM_001078022 XM_005203993
HUGO HGNC:4279
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02007326 DAAA02007327
GenPept
RNA Seq Atlas 539491

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca