Version 5.4
Bos taurus Protein: DLG1
Summary
InnateDB Protein IDBP-685919.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DLG1
Protein Name discs, large homolog 1 (Drosophila)
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000027161
InnateDB Gene IDBG-634119 (DLG1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 63 interaction(s) predicted by orthology.
Predicted by orthology
Total 63 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
GO:0019901 protein kinase binding
GO:0019902 phosphatase binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0032947 protein complex scaffold
GO:0044325 ion channel binding
GO:0097016 L27 domain binding
Biological Process
GO:0001657 ureteric bud development
GO:0001658 branching involved in ureteric bud morphogenesis
GO:0001771 immunological synapse formation
GO:0001935 endothelial cell proliferation
GO:0002088 lens development in camera-type eye
GO:0002369 T cell cytokine production
GO:0007015 actin filament organization
GO:0008104 protein localization
GO:0008284 positive regulation of cell proliferation
GO:0016337 single organismal cell-cell adhesion
GO:0030432 peristalsis
GO:0030838 positive regulation of actin filament polymerization
GO:0030866 cortical actin cytoskeleton organization
GO:0031579 membrane raft organization
GO:0031641 regulation of myelination
GO:0032147 activation of protein kinase activity
GO:0042110 T cell activation
GO:0042130 negative regulation of T cell proliferation
GO:0042391 regulation of membrane potential
GO:0042982 amyloid precursor protein metabolic process
GO:0043268 positive regulation of potassium ion transport
GO:0045930 negative regulation of mitotic cell cycle
GO:0048608 reproductive structure development
GO:0048704 embryonic skeletal system morphogenesis
GO:0048729 tissue morphogenesis
GO:0048745 smooth muscle tissue development
GO:0050680 negative regulation of epithelial cell proliferation
GO:0051898 negative regulation of protein kinase B signaling
GO:0060022 hard palate development
GO:0070830 tight junction assembly
GO:0072659 protein localization to plasma membrane
GO:0090004 positive regulation of establishment of protein localization to plasma membrane
Cellular Component
GO:0001772 immunological synapse
GO:0005605 basal lamina
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005874 microtubule
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0005923 tight junction
GO:0009898 cytoplasmic side of plasma membrane
GO:0014069 postsynaptic density
GO:0016323 basolateral plasma membrane
GO:0016328 lateral plasma membrane
GO:0030054 cell junction
GO:0031253 cell projection membrane
GO:0031594 neuromuscular junction
GO:0033268 node of Ranvier
GO:0035748 myelin sheath abaxonal region
GO:0043219 lateral loop
GO:0045121 membrane raft
GO:0045202 synapse
GO:0048471 perinuclear region of cytoplasm
GO:0070062 extracellular vesicular exosome
GO:0097025 MPP7-DLG1-LIN7 complex
Protein Structure and Domains
PDB ID
InterPro IPR001452 SH3 domain
IPR001478 PDZ domain
IPR008144 Guanylate kinase-like
IPR008145 Guanylate kinase/L-type calcium channel beta subunit
IPR011511 Variant SH3 domain
IPR016313 Disks large 1
IPR019583 PDZ-associated domain of NMDA receptors
IPR019590 Membrane-associated guanylate kinase (MAGUK), PEST domain, N-terminal
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00018
PF14604
PF00595
PF13180
PF00625
PF07653
PF10600
PF10608
PRINTS PR00452
PIRSF PIRSF001741
SMART SM00326
SM00228
SM00072
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1MNQ3
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq
HUGO HGNC:2900
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02001706 DAAA02001707 DAAA02001708 DAAA02001709 DAAA02001710 DAAA02001711 DAAA02001712
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca