Version 5.4
Bos taurus Protein: FANCL
Summary
InnateDB Protein IDBP-686030.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FANCL
Protein Name E3 ubiquitin-protein ligase FANCL
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000007713
InnateDB Gene IDBG-634255 (FANCL)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.
Predicted by orthology
Total 17 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0031625 ubiquitin protein ligase binding
GO:0046872 metal ion binding
Biological Process
GO:0006281 DNA repair
GO:0006513 protein monoubiquitination
GO:0006974 cellular response to DNA damage stimulus
GO:0007276 gamete generation
GO:0042127 regulation of cell proliferation
Cellular Component
GO:0005635 nuclear envelope
GO:0043240 Fanconi anaemia nuclear complex
Protein Structure and Domains
PDB ID
InterPro IPR001841 Zinc finger, RING-type
IPR019162 Fanconi anemia complex, subunit FancL, WD-repeat containing domain
PFAM PF13639
PF14634
PF09765
PRINTS
PIRSF
SMART SM00184
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q2TBN8
UniProt Splice Variant
Entrez Gene 614512
UniGene Bt.64652
RefSeq NP_001069800
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC109882 DAAA02030964 DAAA02030965 DAAA02030966 DAAA02030967 DAAA02030968
GenPept AAI09883

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca