InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: BT.64827

Summary

InnateDB Protein

IDBP-686041.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.64827

Protein Name

cadherin-1 precursor

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000021272

InnateDB Gene

IDBG-634263 (BT.64827)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 140 interaction(s) predicted by orthology.

Predicted by orthology
Total	140 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001948	glycoprotein binding
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0008013	beta-catenin binding
GO:0019903	protein phosphatase binding
GO:0019904	protein domain specific binding
GO:0030506	ankyrin binding
GO:0032794	GTPase activating protein binding
GO:0045295	gamma-catenin binding

Biological Process

GO:0001701	in utero embryonic development
GO:0001829	trophectodermal cell differentiation
GO:0003382	epithelial cell morphogenesis
GO:0007155	cell adhesion
GO:0007156	homophilic cell adhesion
GO:0007605	sensory perception of sound
GO:0016337	single organismal cell-cell adhesion
GO:0016339	calcium-dependent cell-cell adhesion
GO:0019538	protein metabolic process
GO:0022408	negative regulation of cell-cell adhesion
GO:0032880	regulation of protein localization
GO:0033561	regulation of water loss via skin
GO:0042993	positive regulation of transcription factor import into nucleus
GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0045893	positive regulation of transcription, DNA-templated
GO:0050680	negative regulation of epithelial cell proliferation
GO:0051260	protein homooligomerization
GO:0060576	intestinal epithelial cell development
GO:0060662	salivary gland cavitation
GO:0060693	regulation of branching involved in salivary gland morphogenesis
GO:0070830	tight junction assembly
GO:0071230	cellular response to amino acid stimulus
GO:0071285	cellular response to lithium ion
GO:0071681	cellular response to indole-3-methanol
GO:0072659	protein localization to plasma membrane
GO:0090002	establishment of protein localization to plasma membrane
GO:0090090	negative regulation of canonical Wnt signaling pathway
GO:0090102	cochlea development
GO:2000008	regulation of protein localization to cell surface
GO:2001222	regulation of neuron migration

Cellular Component

GO:0005737	cytoplasm
GO:0005802	trans-Golgi network
GO:0005886	plasma membrane
GO:0005911	cell-cell junction
GO:0005912	adherens junction
GO:0005913	cell-cell adherens junction
GO:0005925	focal adhesion
GO:0009898	cytoplasmic side of plasma membrane
GO:0009986	cell surface
GO:0015629	actin cytoskeleton
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0016235	aggresome
GO:0016323	basolateral plasma membrane
GO:0016328	lateral plasma membrane
GO:0016342	catenin complex
GO:0030424	axon
GO:0033268	node of Ranvier
GO:0043219	lateral loop
GO:0043220	Schmidt-Lanterman incisure
GO:0043296	apical junction complex
GO:0043679	axon terminus
GO:0045177	apical part of cell
GO:0048471	perinuclear region of cytoplasm
GO:0070062	extracellular vesicular exosome
GO:0071944	cell periphery

Protein Structure and Domains

PDB ID

InterPro

IPR000233 Cadherin, cytoplasmic domain
IPR002126 Cadherin
IPR014868 Cadherin prodomain
IPR015919 Cadherin-like

PFAM

PF01049
PF00028
PF08758

PRINTS

PR00205

PIRSF

SMART

SM00112
SM01055

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q8HXZ0

UniProt Splice Variant

Entrez Gene

282637

UniGene

Bt.64827

RefSeq

NP_001002763

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

AB037667 DAAA02046698

GenPept

BAC24977