Version 5.4
Bos taurus Protein: DDR1
Summary
InnateDB Protein IDBP-686285.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DDR1
Protein Name discoidin domain receptor family, member 1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000014143
InnateDB Gene IDBG-634478 (DDR1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005518 collagen binding
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0016740 transferase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0038062 protein tyrosine kinase collagen receptor activity
Biological Process
GO:0001558 regulation of cell growth
GO:0001952 regulation of cell-matrix adhesion
GO:0006468 protein phosphorylation
GO:0007155 cell adhesion
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007566 embryo implantation
GO:0008285 negative regulation of cell proliferation
GO:0010715 regulation of extracellular matrix disassembly
GO:0014909 smooth muscle cell migration
GO:0016310 phosphorylation
GO:0018108 peptidyl-tyrosine phosphorylation
GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway
GO:0038083 peptidyl-tyrosine autophosphorylation
GO:0043583 ear development
GO:0044319 wound healing, spreading of cells
GO:0046777 protein autophosphorylation
GO:0060444 branching involved in mammary gland duct morphogenesis
GO:0060749 mammary gland alveolus development
GO:0061302 smooth muscle cell-matrix adhesion
Cellular Component
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0043235 receptor complex
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR000421 Coagulation factor 5/8 C-terminal type domain
IPR000719 Protein kinase domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002290 Serine/threonine/dual specificity protein kinase, catalytic domain
IPR008979 Galactose-binding domain-like
IPR011009 Protein kinase-like domain
IPR020635 Tyrosine-protein kinase, catalytic domain
PFAM PF00754
PF00069
PF07714
PRINTS PR00109
PIRSF
SMART SM00231
SM00220
SM00219
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E1BBP4
UniProt Splice Variant
Entrez Gene 534092
UniGene
RefSeq NP_001069480
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02055395 DAAA02055396
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca