InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: LEPREL1

Summary

InnateDB Protein

IDBP-686311.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

LEPREL1

Protein Name

prolyl 3-hydroxylase 2

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000027999

InnateDB Gene

IDBG-634523 (LEPREL1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005506	iron ion binding
GO:0016491	oxidoreductase activity
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0016706	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0019797	procollagen-proline 3-dioxygenase activity
GO:0031418	L-ascorbic acid binding

Biological Process

GO:0008285	negative regulation of cell proliferation
GO:0019511	peptidyl-proline hydroxylation
GO:0032963	collagen metabolic process
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005604	basement membrane
GO:0005783	endoplasmic reticulum
GO:0005794	Golgi apparatus

Protein Structure and Domains

PDB ID

InterPro

IPR005123 Oxoglutarate/iron-dependent dioxygenase
IPR006620 Prolyl 4-hydroxylase, alpha subunit

PFAM

PF03171
PF13640

PRINTS

PIRSF

SMART

SM00702

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

A6QLY3

UniProt Splice Variant

Entrez Gene

511799

UniGene

Bt.30683

RefSeq

NP_001093815

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC148129 DAAA02001802 DAAA02001803

GenPept

AAI48130