InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: CASQ2

Summary

InnateDB Protein

IDBP-686325.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CASQ2

Protein Name

calsequestrin 2 (cardiac muscle)

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000015285

InnateDB Gene

IDBG-634546 (CASQ2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005509	calcium ion binding
GO:0005515	protein binding

Biological Process

GO:0002027	regulation of heart rate
GO:0010649	regulation of cell communication by electrical coupling
GO:0010881	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
GO:0043267	negative regulation of potassium ion transport
GO:0051208	sequestering of calcium ion
GO:0051258	protein polymerization
GO:0060048	cardiac muscle contraction
GO:0060306	regulation of membrane repolarization
GO:0071313	cellular response to caffeine
GO:1901017	negative regulation of potassium ion transmembrane transporter activity

Cellular Component

GO:0005622	intracellular
GO:0005737	cytoplasm
GO:0030018	Z disc

Protein Structure and Domains

PDB ID

InterPro

IPR001393 Calsequestrin
IPR012336 Thioredoxin-like fold

PFAM

PF01216
PF13098
PF13192
PF13462
PF13905

PRINTS

PR00312

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q3MHM1

UniProt Splice Variant

Entrez Gene

528555

UniGene

Bt.30022

RefSeq

NP_001030451

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC105185 DAAA02007427 DAAA02007428

GenPept

AAI05186