InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: AHSG

Summary

InnateDB Protein

IDBP-686463.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

AHSG

Protein Name

Alpha-2-HS-glycoprotein

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000000673

InnateDB Gene

IDBG-634683 (AHSG)

Protein Structure

UniProt Annotation

Function

Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Suggested to have lymphocyte stimulating properties, lipid binding capability and to bind thyroid hormone.

Subcellular Localization

Secreted.

Disease Associations

Tissue Specificity

Liver and bone.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	18 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004869	cysteine-type endopeptidase inhibitor activity
GO:0005515	protein binding

Biological Process

GO:0001503	ossification
GO:0006953	acute-phase response
GO:0010951	negative regulation of endopeptidase activity
GO:0030500	regulation of bone mineralization
GO:0030502	negative regulation of bone mineralization
GO:0050727	regulation of inflammatory response
GO:0050766	positive regulation of phagocytosis

Cellular Component

GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0005886	plasma membrane
GO:0031982	vesicle
GO:0065010	extracellular membrane-bounded organelle
GO:0070062	extracellular vesicular exosome
GO:0072562	blood microparticle