InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: RRM1

Summary

InnateDB Protein

IDBP-686487.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RRM1

Protein Name

ribonucleoside-diphosphate reductase M1 chain

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000017428

InnateDB Gene

IDBG-634697 (RRM1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 27 interaction(s) predicted by orthology.

Predicted by orthology
Total	27 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016491	oxidoreductase activity
GO:0017076	purine nucleotide binding

Biological Process

GO:0006260	DNA replication
GO:0009263	deoxyribonucleotide biosynthetic process
GO:0051259	protein oligomerization
GO:0051290	protein heterotetramerization
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005737	cytoplasm
GO:0005971	ribonucleoside-diphosphate reductase complex
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR000788 Ribonucleotide reductase large subunit, C-terminal
IPR005144 ATP-cone
IPR008926 Ribonucleotide reductase R1 subunit, N-terminal
IPR013346 Ribonucleotide reductase, class I , alpha subunit
IPR013509 Ribonucleotide reductase large subunit, N-terminal

PFAM

PF02867
PF03477
PF00317

PRINTS

PR01183

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite