InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: BT.41831

Summary

InnateDB Protein

IDBP-686620.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.41831

Protein Name

homeodomain-interacting protein kinase 1

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000015051

InnateDB Gene

IDBG-634810 (BT.41831)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.

Predicted by orthology
Total	15 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016772	transferase activity, transferring phosphorus-containing groups

Biological Process

GO:0006468	protein phosphorylation
GO:0007224	smoothened signaling pathway
GO:0008284	positive regulation of cell proliferation
GO:0009952	anterior/posterior pattern specification
GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway
GO:0010842	retina layer formation
GO:0016926	protein desumoylation
GO:0030182	neuron differentiation
GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0048596	embryonic camera-type eye morphogenesis
GO:0060059	embryonic retina morphogenesis in camera-type eye
GO:0060235	lens induction in camera-type eye
GO:0061072	iris morphogenesis
GO:0072577	endothelial cell apoptotic process
GO:0097191	extrinsic apoptotic signaling pathway

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0016605	PML body
GO:0016607	nuclear speck

Protein Structure and Domains

PDB ID

InterPro

IPR000719 Protein kinase domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002290 Serine/threonine/dual specificity protein kinase, catalytic domain
IPR011009 Protein kinase-like domain
IPR020635 Tyrosine-protein kinase, catalytic domain

PFAM

PF00069
PF07714

PRINTS

PR00109

PIRSF

SMART

SM00220
SM00219

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt