InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: EPHB3

Summary

InnateDB Protein

IDBP-686777.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

EPHB3

Protein Name

EPH receptor B3

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000006988

InnateDB Gene

IDBG-634976 (EPHB3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.

Predicted by orthology
Total	10 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0004672	protein kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0005003	ephrin receptor activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0008046	axon guidance receptor activity
GO:0016301	kinase activity
GO:0016740	transferase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups

Biological Process

GO:0001525	angiogenesis
GO:0001655	urogenital system development
GO:0006468	protein phosphorylation
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007411	axon guidance
GO:0007413	axonal fasciculation
GO:0016310	phosphorylation
GO:0016477	cell migration
GO:0018108	peptidyl-tyrosine phosphorylation
GO:0021952	central nervous system projection neuron axonogenesis
GO:0022038	corpus callosum development
GO:0022407	regulation of cell-cell adhesion
GO:0031290	retinal ganglion cell axon guidance
GO:0032314	regulation of Rac GTPase activity
GO:0034446	substrate adhesion-dependent cell spreading
GO:0043088	regulation of Cdc42 GTPase activity
GO:0046777	protein autophosphorylation
GO:0048013	ephrin receptor signaling pathway
GO:0048538	thymus development
GO:0048546	digestive tract morphogenesis
GO:0050770	regulation of axonogenesis
GO:0051965	positive regulation of synapse assembly
GO:0060021	palate development
GO:0060996	dendritic spine development
GO:0060997	dendritic spine morphogenesis

Cellular Component

GO:0005887	integral component of plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000719 Protein kinase domain
IPR001090 Ephrin receptor ligand binding domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR001660 Sterile alpha motif domain
IPR002290 Serine/threonine/dual specificity protein kinase, catalytic domain
IPR003961 Fibronectin, type III
IPR008979 Galactose-binding domain-like
IPR009030 Insulin-like growth factor binding protein, N-terminal
IPR011009 Protein kinase-like domain
IPR011510 Sterile alpha motif, type 2
IPR011641 Tyrosine-protein kinase ephrin type A/B receptor-like
IPR013761 Sterile alpha motif/pointed domain
IPR016257 Ephrin receptor type-A /type-B
IPR020635 Tyrosine-protein kinase, catalytic domain
IPR021129 Sterile alpha motif, type 1

PFAM