InnateDB Protein
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IDBP-686796.2
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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CAPZA1
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Protein Name
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F-actin-capping protein subunit alpha-1
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Synonyms
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Species
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Bos taurus
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Ensembl Protein
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ENSBTAP00000042551
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InnateDB Gene
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IDBG-634999 (CAPZA1)
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Protein Structure
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Function |
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity). {ECO:0000250}.
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Subcellular Localization |
Cytoplasm, cytoskeleton {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 56 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
56 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR002189
F-actin-capping protein subunit alpha
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PFAM |
PF01267
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PRINTS |
PR00191
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
A4FUA8
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PhosphoSite |
PhosphoSite-
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
534656
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UniGene |
Bt.45960
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RefSeq |
NP_001076949
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HUGO |
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OMIM |
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CCDS |
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HPRD |
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IMGT |
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EMBL |
BC114648
BT030727
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GenPept |
AAI14649
ABS45043
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