Version 5.4
Bos taurus Gene: CAPZA1
Summary
InnateDB Gene IDBG-634999.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CAPZA1
Gene Name F-actin-capping protein subunit alpha-1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000014295
Encoded Proteins
IDBP-686796
F-actin-capping protein subunit alpha-1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000116489:
CAPZA1 is a member of the F-actin capping protein alpha subunit family. This gene encodes the alpha subunit of the barbed-end actin binding protein. The protein regulates growth of the actin filament by capping the barbed end of growing actin filaments. [provided by RefSeq, Jul 2008]
CAPZA1 is a member of the F-actin capping protein alpha subunit family. This gene encodes the alpha subunit of the barbed-end actin binding protein. The protein regulates growth of the actin filament by capping the barbed end of growing actin filaments. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:30810109-30854190
Strand Reverse strand
Band
Transcripts
ENSBTAT00000045136 ENSBTAP00000042551
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 56 interaction(s) predicted by orthology.
Predicted by orthology
Total 56 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005515 protein binding
GO:0051015 actin filament binding
Biological Process
GO:0030036 actin cytoskeleton organization
GO:0051016 barbed-end actin filament capping
GO:0051693 actin filament capping
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005911 cell-cell junction
GO:0008290 F-actin capping protein complex
GO:0016020 membrane
GO:0030863 cortical cytoskeleton
GO:0070062 extracellular vesicular exosome
GO:0071203 WASH complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000116489
View Gene Order
ENSMUSG00000070372
View Gene Order
Pathways
NETPATH
REACTOME
REACT_215067
Factors involved in megakaryocyte development and platelet production pathway
REACT_212196
Hemostasis pathway
REACT_213138
Immune System pathway
REACT_204725
Advanced glycosylation endproduct receptor signaling pathway
REACT_216714
Innate Immune System pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_25195
Advanced glycosylation endproduct receptor signaling pathway
REACT_24970
Factors involved in megakaryocyte development and platelet production pathway
REACT_6802
Innate Immune System pathway
REACT_6900
Immune System pathway
REACT_604
Hemostasis pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt A4FUA8
TrEMBL
UniProt Splice Variant
Entrez Gene 534656
UniGene Bt.45960
RefSeq NM_001083480
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC114648 BT030727
GenPept AAI14649 ABS45043
RNA Seq Atlas 534656

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca