InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: TNFSF13

Summary

InnateDB Protein

IDBP-686808.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TNFSF13

Protein Name

tumor necrosis factor ligand superfamily member 13

Synonyms

APRIL;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000000141

InnateDB Gene

IDBG-635008 (TNFSF13)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005125	cytokine activity
GO:0005164	tumor necrosis factor receptor binding
GO:0005515	protein binding

Biological Process

GO:0002426	immunoglobulin production in mucosal tissue
GO:0002636	positive regulation of germinal center formation
GO:0006955	immune response
GO:0008284	positive regulation of cell proliferation
GO:0016064	immunoglobulin mediated immune response
GO:0048298	positive regulation of isotype switching to IgA isotypes
GO:0050776	regulation of immune response

Cellular Component

GO:0005615	extracellular space
GO:0005737	cytoplasm
GO:0009897	external side of plasma membrane
GO:0016020	membrane
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR006052 Tumour necrosis factor domain
IPR008983 Tumour necrosis factor-like domain

PFAM

PF00229

PRINTS

PIRSF

SMART

SM00207

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q3ZBM0

UniProt Splice Variant

Entrez Gene

538567

UniGene

Bt.49553

RefSeq

NP_001029819

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC103223 DAAA02048793 FJ539091

GenPept

AAI03224 ACT66298