Version 5.4
Bos taurus Protein: ZNRD1
Summary
InnateDB Protein IDBP-686901.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZNRD1
Protein Name DNA-directed RNA polymerase I subunit RPA12
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000042491
InnateDB Gene IDBG-635100 (ZNRD1)
Protein Structure
UniProt Annotation
Function DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors.
Subcellular Localization Nucleus, nucleolus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
Predicted by orthology
Total 15 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001054 RNA polymerase I activity
GO:0003676 nucleic acid binding
GO:0003899 DNA-directed RNA polymerase activity
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006363 termination of RNA polymerase I transcription
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005736 DNA-directed RNA polymerase I complex
Protein Structure and Domains
PDB ID
InterPro IPR001222 Zinc finger, TFIIS-type
PFAM PF01096
PRINTS
PIRSF
SMART SM00440
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q1RMP0
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 535288
UniGene Bt.1771
RefSeq NP_001039865
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC114799
GenPept AAI14800

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca