InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: DYNC1H1

Summary

InnateDB Protein

IDBP-686902.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DYNC1H1

Protein Name

dynein, cytoplasmic 1, heavy chain 1

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000042130

InnateDB Gene

IDBG-634680 (DYNC1H1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 95 interaction(s) predicted by orthology.

Predicted by orthology
Total	95 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003777	microtubule motor activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016887	ATPase activity
GO:0017111	nucleoside-triphosphatase activity
GO:0044822	poly(A) RNA binding
GO:0051959	dynein light intermediate chain binding

Biological Process

GO:0006200	ATP catabolic process
GO:0007018	microtubule-based movement
GO:0008152	metabolic process
GO:0033962	cytoplasmic mRNA processing body assembly
GO:0034063	stress granule assembly

Cellular Component

GO:0005737	cytoplasm
GO:0005813	centrosome
GO:0005874	microtubule
GO:0016020	membrane
GO:0030175	filopodium
GO:0030286	dynein complex
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR003593 AAA+ ATPase domain
IPR004273 Dynein heavy chain domain
IPR010987 Glutathione S-transferase, C-terminal-like
IPR011704 ATPase, dynein-related, AAA domain
IPR013594 Dynein heavy chain, domain-1
IPR013602 Dynein heavy chain, domain-2
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF03028
PF07728
PF08385
PF08393

PRINTS

PIRSF

SMART

SM00382

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite