InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: INPPL1

Summary

InnateDB Protein

IDBP-686910.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

INPPL1

Protein Name

inositol polyphosphate phosphatase-like 1

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000025510

InnateDB Gene

IDBG-635082 (INPPL1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 58 interaction(s) predicted by orthology.

Predicted by orthology
Total	58 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0042169	SH2 domain binding

Biological Process

GO:0001958	endochondral ossification
GO:0006006	glucose metabolic process
GO:0006661	phosphatidylinositol biosynthetic process
GO:0006897	endocytosis
GO:0007015	actin filament organization
GO:0008285	negative regulation of cell proliferation
GO:0009791	post-embryonic development
GO:0010629	negative regulation of gene expression
GO:0032868	response to insulin
GO:0044255	cellular lipid metabolic process
GO:0046856	phosphatidylinositol dephosphorylation
GO:0097178	ruffle assembly

Cellular Component

GO:0005737	cytoplasm
GO:0005794	Golgi apparatus
GO:0005886	plasma membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000300 Inositol polyphosphate-related phosphatase
IPR000980 SH2 domain
IPR001660 Sterile alpha motif domain
IPR005135 Endonuclease/exonuclease/phosphatase
IPR011510 Sterile alpha motif, type 2
IPR013761 Sterile alpha motif/pointed domain
IPR021129 Sterile alpha motif, type 1

PFAM

PF00017
PF14633
PF03372
PF14529
PF07647
PF00536

PRINTS

PR00401

PIRSF

SMART

SM00128
SM00252
SM00454

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt