InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: ANXA4

Summary

InnateDB Protein

IDBP-687756.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ANXA4

Protein Name

Annexin A4

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000001463

InnateDB Gene

IDBG-635876 (ANXA4)

Protein Structure

UniProt Annotation

Function

May play a role in alveolar type II cells through interaction with the surfactant protein SFTPA1 (SP-A).

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.

Predicted by orthology
Total	13 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005509	calcium ion binding
GO:0005544	calcium-dependent phospholipid binding
GO:0008201	heparin binding
GO:0030246	carbohydrate binding
GO:0035374	chondroitin sulfate binding
GO:0042802	identical protein binding
GO:0048306	calcium-dependent protein binding
GO:0051059	NF-kappaB binding

Biological Process

GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0030855	epithelial cell differentiation
GO:0032088	negative regulation of NF-kappaB transcription factor activity
GO:2000483	negative regulation of interleukin-8 secretion

Cellular Component

GO:0005634	nucleus
GO:0005886	plasma membrane
GO:0009986	cell surface
GO:0012506	vesicle membrane
GO:0016324	apical plasma membrane
GO:0031965	nuclear membrane
GO:0042584	chromaffin granule membrane
GO:0048471	perinuclear region of cytoplasm
GO:0070062	extracellular vesicular exosome