InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: TRIM24

Summary

InnateDB Protein

IDBP-687793.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TRIM24

Protein Name

tripartite motif containing 24

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000003151

InnateDB Gene

IDBG-635873 (TRIM24)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 40 interaction(s) predicted by orthology.

Predicted by orthology
Total	40 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0002039	p53 binding
GO:0003682	chromatin binding
GO:0003713	transcription coactivator activity
GO:0004672	protein kinase activity
GO:0004842	ubiquitin-protein transferase activity
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0016922	ligand-dependent nuclear receptor binding
GO:0034056	estrogen response element binding
GO:0043565	sequence-specific DNA binding
GO:0046872	metal ion binding
GO:0070577	lysine-acetylated histone binding

Biological Process

GO:0006468	protein phosphorylation
GO:0008285	negative regulation of cell proliferation
GO:0010628	positive regulation of gene expression
GO:0030163	protein catabolic process
GO:0031647	regulation of protein stability
GO:0042981	regulation of apoptotic process
GO:0045892	negative regulation of transcription, DNA-templated
GO:0045893	positive regulation of transcription, DNA-templated
GO:0046777	protein autophosphorylation
GO:0055074	calcium ion homeostasis
GO:0070562	regulation of vitamin D receptor signaling pathway
GO:0071391	cellular response to estrogen stimulus
GO:1901796	regulation of signal transduction by p53 class mediator

Cellular Component

GO:0005622	intracellular
GO:0005634	nucleus
GO:0005719	nuclear euchromatin
GO:0005726	perichromatin fibrils
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR000315 Zinc finger, B-box
IPR001487 Bromodomain
IPR001841 Zinc finger, RING-type
IPR001965 Zinc finger, PHD-type
IPR003649 B-box, C-terminal
IPR011011 Zinc finger, FYVE/PHD-type
IPR019787 Zinc finger, PHD-finger

PFAM

PF00643
PF00439
PF13639
PF14634
PF00628

PRINTS

PR00503

PIRSF

SMART

SM00336
SM00297
SM00184
SM00249
SM00502

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt