InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: PAN2

Summary

InnateDB Protein

IDBP-687999.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PAN2

Protein Name

PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)

Synonyms

USP52;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000053637

InnateDB Gene

IDBG-636091 (PAN2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 291 interaction(s) predicted by orthology.

Predicted by orthology
Total	291 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000175	3'-5'-exoribonuclease activity
GO:0003676	nucleic acid binding
GO:0004527	exonuclease activity
GO:0004535	poly(A)-specific ribonuclease activity
GO:0005515	protein binding
GO:0036459	ubiquitinyl hydrolase activity

Biological Process

GO:0006511	ubiquitin-dependent protein catabolic process
GO:0090305	nucleic acid phosphodiester bond hydrolysis

Cellular Component

GO:0000932	cytoplasmic mRNA processing body
GO:0031251	PAN complex

Protein Structure and Domains

PDB ID

InterPro

IPR001394 Peptidase C19, ubiquitin carboxyl-terminal hydrolase
IPR006055 Exonuclease
IPR012337 Ribonuclease H-like domain
IPR013520 Exonuclease, RNase T/DNA polymerase III
IPR017986 WD40-repeat-containing domain
IPR028889 Ubiquitin carboxyl-terminal hydrolase-like domain

PFAM

PF00443
PF00929

PRINTS

PIRSF

SMART

SM00479

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite