|
InnateDB Protein
|
IDBP-68811.6
|
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
|
Gene Symbol
|
GGT7
|
|
Protein Name
|
gamma-glutamyltransferase 7
|
|
Synonyms
|
D20S101; dJ18C9.2; GGT4; GGTL3; GGTL5;
|
|
Species
|
Homo sapiens
|
|
Ensembl Protein
|
ENSP00000338964
|
|
InnateDB Gene
|
IDBG-68807 (GGT7)
|
|
Protein Structure
|
|
| Function |
Cleaves glutathione conjugates. {ECO:0000250}.
|
| Subcellular Localization |
Membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
|
| Disease Associations |
|
| Tissue Specificity |
Widely expressed, but at low level, except in the airway epithelial cells. Detected in brain, heart, kidney, liver, lung, spleen, testis and trachea.
|
| Comments |
|
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
| Experimentally validated |
| Total |
3
[view]
|
| Protein-Protein |
3
[view]
|
| Protein-DNA |
0
|
| Protein-RNA |
0
|
| DNA-DNA |
0
|
| RNA-RNA |
0
|
| DNA-RNA |
0
|
|
|
|
Molecular Function |
| Accession |
GO Term |
|
GO:0003840
|
gamma-glutamyltransferase activity
|
|
GO:0036374
|
glutathione hydrolase activity
|
|
| Biological Process |
|
| Cellular Component |
|
GO:0016021
|
integral component of membrane
|
|
GO:0031362
|
anchored component of external side of plasma membrane
|
|
| PDB ID |
|
| InterPro |
IPR000101
Gamma-glutamyltranspeptidase
IPR029055
Nucleophile aminohydrolases, N-terminal
|
| PFAM |
PF01019
|
| PRINTS |
PR01210
|
| PIRSF |
|
| SMART |
|
| TIGRFAMs |
|
| Modification |
|
| SwissProt |
Q9UJ14
|
| PhosphoSite |
PhosphoSite-Q9UJ14
|
| TrEMBL |
A4FU32
|
| UniProt Splice Variant |
|
| Entrez Gene |
2686
|
| UniGene |
Hs.433738
|
| RefSeq |
NP_821158
|
| HUGO |
HGNC:4259
|
| OMIM |
612342
|
| CCDS |
CCDS13242
|
| HPRD |
07488
|
| IMGT |
|
| EMBL |
AK090413
AK097100
AL049709
AY138815
BC033745
BC101371
BC101372
|
| GenPept |
AAH33745
AAI01372
AAI01373
AAN15928
BAC03394
BAC04950
CAB61787
|
|
|
|
Version 5.4