InnateDB Protein
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IDBP-688363.2
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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LMO2
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Protein Name
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Rhombotin-2
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Synonyms
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Species
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Bos taurus
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Ensembl Protein
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ENSBTAP00000009126
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InnateDB Gene
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IDBG-636445 (LMO2)
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Protein Structure
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Function |
Acts with TAL1/SCL to regulate red blood cell development. Also acts with LDB1 to maintain erythroid precursors in an immature state.
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Subcellular Localization |
Nucleus {ECO:0000305}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 49 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
49 [view]
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Molecular Function |
Accession |
GO Term |
GO:0000977
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RNA polymerase II regulatory region sequence-specific DNA binding
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GO:0000981
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sequence-specific DNA binding RNA polymerase II transcription factor activity
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GO:0001102
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RNA polymerase II activating transcription factor binding
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GO:0001190
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RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription
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GO:0001228
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RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
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GO:0003677
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DNA binding
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GO:0003682
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chromatin binding
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GO:0005515
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protein binding
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GO:0008270
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zinc ion binding
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GO:0043425
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bHLH transcription factor binding
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GO:0046872
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metal ion binding
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GO:0048037
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cofactor binding
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GO:0070888
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E-box binding
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Biological Process |
GO:0035162
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embryonic hemopoiesis
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GO:0042789
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mRNA transcription from RNA polymerase II promoter
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GO:0045647
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negative regulation of erythrocyte differentiation
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GO:0045944
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positive regulation of transcription from RNA polymerase II promoter
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GO:0097067
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cellular response to thyroid hormone stimulus
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Cellular Component |
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PDB ID |
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InterPro |
IPR001781
Zinc finger, LIM-type
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PFAM |
PF00412
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PRINTS |
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PIRSF |
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SMART |
SM00132
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TIGRFAMs |
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Modification |
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SwissProt |
Q1LZ94
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PhosphoSite |
PhosphoSite-
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
614876
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UniGene |
Bt.17081
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RefSeq |
NP_001069820
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HUGO |
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OMIM |
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CCDS |
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HPRD |
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IMGT |
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EMBL |
BC116134
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GenPept |
AAI16135
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