Bos taurus Protein: GFI1
Summary
InnateDB Protein IDBP-688508.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GFI1
Protein Name growth factor independent 1 transcription repressor
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000022231
InnateDB Gene IDBG-636580 (GFI1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 49 interaction(s) predicted by orthology.
Predicted by orthology
Total 49 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001078 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0003676 nucleic acid binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0044212 transcription regulatory region DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0007638 mechanosensory behavior
GO:0009996 negative regulation of cell fate specification
GO:0010956 negative regulation of calcidiol 1-monooxygenase activity
GO:0010977 negative regulation of neuron projection development
GO:0032088 negative regulation of NF-kappaB transcription factor activity
GO:0034121 regulation of toll-like receptor signaling pathway
GO:0042472 inner ear morphogenesis
GO:0042491 auditory receptor cell differentiation
GO:0042660 positive regulation of cell fate specification
GO:0045165 cell fate commitment
GO:0045892 negative regulation of transcription, DNA-templated
GO:0070105 positive regulation of interleukin-6-mediated signaling pathway
GO:0071222 cellular response to lipopolysaccharide
Cellular Component
GO:0005634 nucleus
GO:0016363 nuclear matrix
GO:0016604 nuclear body
GO:0017053 transcriptional repressor complex
Protein Structure and Domains
PDB ID
InterPro IPR007087 Zinc finger, C2H2
IPR015880 Zinc finger, C2H2-like
PFAM PF00096
PRINTS
PIRSF
SMART SM00355
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1MPJ9
UniProt Splice Variant
Entrez Gene 100139952
UniGene Bt.28572
RefSeq NP_001178241
HUGO HGNC:4237
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02007904
GenPept